KnowMED Inc.

KnowMED Knowledge Analytic Platform

Understanding, diagnosing, treating, and preventing human disease requires the integration of information and knowledge from all levels of biology including molecules, tissues, organ systems, individuals and populations.

 Heterogeneous information from semantically and schematically disparate sources must benormalized, integrated and mapped to an array of biomedical vocabulary systems. Integrated data need to be repurposed to support research and practical applications across different principles, and among different communities, without losing or distorting the semantics and the context of the original data. Sensitive health information needs to be shared and exchanged in an environment that is distributed in time and space and among boundaries of different jurisdictions, organizations, departments, and information systems. All these operations must comply with organizational policies and regulations relating to the proper use of data (consent management, accountability, confidentiality, audit, and control).

Knowmed Knowledge Analytic Platform is a suite of semantic solutions and a technology portfolio that enable KnowMED to implement dynamically adaptable health information systems that address all axis of complexity in health information interoperability.

Architectural Perspective:

KnowMED application design architecture rests upon triangulation of 3 modern systems concepts: a) using goal-directed, user centric task analysis to identify operational information representation and information retrieval requirements along with all dependencies and governing cultural, regulatory and environmental constraints; b) using knowledge engineering and modeling techniques to create formal models (ontologies) that provides context for computational interpretation of information available to the system; c) deploying an array of Services that are invoked on demand to implement information interpretation processes using context and information provided by the ontologies.

This high level architecture conceptualizes an iterative process where new information are described reusing and extending existing ontologies or by constructing new ones, and are implemented by reusing or extending existing Services or by adding new services to the portfolio of system Services. KnowMED technologies enable integrated and organically growing architectures that maximizes utility of all computational resources by capitalizing on reuse of existing models and Services, and scale up to meet future challenges by employing technological frameworks that are designed for agility and dynamic evolution as well as interoperability and integration.

KnowMED architecture leverages Internet based technologies such as the Semantic Web and SOA for integration and interoperability on a heterogeneous environment that is distributed in time and space. This enables construction of a distributed and collaborative consortium, where participants contribute their data along with ontologies that describe them and Services to access and interpret them, and benefit from using information, ontologies and Services that are shared within that consortium. This is an extension and improvement to the traditional SOA where Services are the only shared and reusable resources. KnowMED technology help present the data, the knowledge and the Services as reusable, shared and distributed resources, as ingredients of designing ultra large scale, federated and interoperable systems.